FISH

    

Fluorescence in situ hybridization (FISH)

This page provides links to helpful resources for understanding how fluorescence in situ hybridization (FISH) works and some of its common applications. 

General Resources

Introduction to FISH

Technical standards and guidelines

FISH BAC probe selection using UCSC Genome Browser

Helpful readings and resources

General Resources

Introduction to FISH

Introduction to FISH

A short presentation providing information about how FISH works, different types of FISH probes, and examples of abnormalities that can be detected by FISH.


Technical standards and guidelines

American College of Medical Genetics technical standards and guidelines

Section E9 of the American College of Medical Genetics technical standards and guidelines: Fluorescence in situ hybridization (PMID: 21738013)


FISH BAC probe selection using the UCSC Genome Browser

FISH BAC probe selection using the UCSC Genome Browser

This document shows how to use the Genome Browser to identify potential FISH probe locations within a region of interest (for example, for follow-up of microarray findings).


Helpful readings and resources

Wolff, D.J. (2013). Fluorescence In Situ Hybridization (FISH). In: Gersen, S., Keagle, M. (eds) The Principles of Clinical Cytogenetics. 


Back to Top   



Notice and Disclaimer/Limitation of Liability of Resource Use
Data and information obtained from the Cancer Genomics Consortium (CGC) and the Geneticist Toolkit are provided as an educational resource only; they should not be used as a stand-alone resource for clinical decision making or reporting, as they may contain errors or omissions. Review of the data by an appropriately trained medical professional is required for clinical reporting. 
Some of these resource pages may include links to content created by commercial entities and/or which require a fee for service; the inclusion of such material is meant for educational purposes only and does not represent an endorsement of these entities by the CGC. 
The CGC and all participating entities make no representation or warranty, express or implied, including without limitation any warranties of merchantability or fitness for a particular purpose or warranties as to the identity or ownership of data or information, the quality, accuracy or completeness of data or information, or that the use of such data or information will not infringe any patent, intellectual property or proprietary rights of any party. The CGC shall not be liable for any claim for any and all loss, harm, illness or other damage or injury arising from access to or use of data or information howsoever caused, including without limitation, any direct, indirect, incidental, exemplary, special or consequential damages, even if advised of the possibility of such damages. The data and information obtained from the Geneticist Toolkit shall not be used as a substitute for the user's skills, expertise and experience.